Matthew 20:22,23
But Jesus answered and said, You don't know what you're asking. Are you able to drink of the cup that I will drink of, and be baptized with the baptism that I am baptized with?
They say to him, We are able. 3 And he said to them, You will drink indeed of my cup, and be baptized with the baptism that I am baptized with:
26:27 And he took the cup, and gave thanks, and gave it to them, saying, Drink you all of it; 28 for this is my blood of the new testament, which is shed for many for the remission of sins.
42: O my Father, if this cup may not pass away from me, except I drink it, your will be done.
AA 542.1 (The Acts of the Apostles)
The disciples recalled Jesus' mysterious words pointing to trial and suffering, yet answered confidently, “We are able.” They would count it highest honor to prove their loyalty by sharing all that was to befall their Lord.
AA 542.2 (The Acts of the Apostles)
Before Him a cross instead of a throne, two malefactors His companions at His right hand and at His left. James and John were to be sharers with their Master in suffering—the one, destined to swift-coming death by the sword; the other, longest of all the disciples to follow his Master in labor and reproach and persecution. “But to sit on My right hand, and on My left,” He continued, “is not Mine to give, but it will be given to them for whom it is prepared of My Father.” Matthew 20:21-23.
The words of the Saviour were borne to the ears of the drowsy disciples, “O My Father, if this cup may not pass away from Me, except I drink it, your will be done.”
EGW 2002--(A Call To Stand Apart)
Turning away, Jesus sought again His retreat, and fell prostrate, overcome by the horror of a great darkness. The humanity of the Son of God trembled in that trying hour. He prayed not now for His disciples that their faith might not fail, but for His own tempted, agonized soul. The awful moment had come—that moment which was to decide the destiny of the world. The fate of humanity trembled in the balance.
Christ might even now refuse to drink the cup apportioned to guilty man. It was not yet too late. He might wipe the bloody sweat from His brow, and leave man to perish in his iniquity. He might say, Let the transgressor receive the penalty of his sin, and I will go back to My Father. Will the Son of God drink the bitter cup of humiliation and agony? Will the innocent suffer the consequences of the curse of sin, to save the guilty? The words fall tremblingly from the pale lips of Jesus, “O My Father, if this cup may not pass away from Me, except I drink it, your will be done.”
EGW 2002--(A Call To Stand Apart)
He feared that sin was so offensive to God that Their separation was to be eternal. Christ felt the anguish which the sinner will feel when mercy will no longer plead for the guilty race. It was the sense of sin, bringing the Father’s wrath upon Him as man’s substitute, that made the cup He drank so bitter, and broke the heart of the Son of God.. kingdom of grace was instituted immediately after the fall of man, when a plan was devised for the redemption of the guilty race.

It then existed in the purpose and by the promise of God; and through faith, men could become its subjects. Yet it was not actually established until the death of Christ. Even after entering upon His earthly mission, the Saviour, wearied with the stubbornness and ingratitude of men, might have drawn back from the sacrifice of Calvary. In Gethsemane the cup of woe trembled in His hand.

But when the Saviour yielded up His life, and with His expiring breath cried out, “It is finished,” then the fulfillment of the plan of redemption was assured. The promise of salvation made to the sinful pair in Eden was ratified. The kingdom of grace, which had before existed by the promise of God, was then established.
Will I drink the cup willingly for my Lord? Matthew 10:39
He that find his life shall lose it: and he that lose his life for my sake will find it.
Matthew 10:38
And he that take not his cross, and follow after me, is not worthy of me.